

🧠 Elevate your mind, own your day — the smart way to stay ahead!
Host Defense Lion's Mane supplement offers 120 organic, non-GMO capsules formulated with mushroom mycelium to support brain health, focus, memory, and immune function. Developed by expert mycologist Paul Stamets, this trusted formula is designed for daily use to enhance cognitive clarity and nervous system support, making it a top choice for professionals seeking natural mental performance enhancement.







| ASIN | B00OVF9DVM |
| Best Sellers Rank | #2,834 in Health & Household ( See Top 100 in Health & Household ) #9 in Mushrooms Herbal Supplements |
| Customer Reviews | 4.6 4.6 out of 5 stars (14,783) |
| Date First Available | July 16, 2014 |
| Is Discontinued By Manufacturer | No |
| Item model number | NCHE120 |
| Manufacturer | Host Defense |
| Product Dimensions | 2.31 x 2.31 x 4.5 inches; 0.04 ounces |
S**R
THESE WORK! great supplement amount.
I am thrilled with my experience using these Lion's Mane mushroom supplements! They have truly made a noticeable difference in my cognitive clarity and mental focus. I have been taking them for a year now, the quality of the supplement is excellent, and I feel more alert and energized throughout the day. I appreciate that it's a natural way to support brain health and boost my overall well-being. Highly recommend to anyone looking to enhance their mental performance and support their nervous system naturally! The amount of actual lions mane in these is what is suggested to actually make a difference. I absolutely notice if I miss a month. No weird after taste.
A**R
Great supplement
Awesome product. It helps us sleep better. It has improved our memory and congnitive functions😘. Absolutely love it 😘😘
N**�
Focus feels sharper, mind feels lighter — love it
I started taking Host Defense Lion’s Mane to help with focus and brain fog, and after a couple of weeks, I genuinely felt more mentally sharp and clear-headed. It’s subtle, but powerful — no jitters, no crash, just steady cognitive support. I also love that it’s made from organic mushrooms and backed by mycologist Paul Stamets — it feels good knowing it's clean and well-sourced. Bonus: it supports nervous system and immune health, so it’s doing more than just boosting brainpower. If you’re looking for a natural way to support memory, focus, and overall mental wellness, this one’s a keeper.
P**R
Improved focus and concentration playing pickleball.
Excellent Lion Mane. Bought for wife with memory issues. I also take them and noticed my focus an concentration improved playing pickleball at 71 years old. Recommended by a friend that has used this for years.
J**R
great benefits
just started this new brand
H**I
I Absolutely Love This Supplement – Clearer Mind, Better Focus!
Host Defense Lion’s Mane has been a total game-changer for me. I started taking it to help with focus and mental clarity—and within about a week, I noticed a real difference. My brain fog started to lift, and my ability to stay on task noticeably improved. I feel more present and mentally sharp throughout the day. What makes me feel confident is the quality and integrity behind the brand. Paul Stamets and the Host Defense team are serious about mushroom science—this isn’t some generic powder. It’s organic, sustainably grown, and made in the USA, which gives me peace of mind. The capsules are easy on the stomach, and I love that it’s a whole mushroom mycelium extract, not just isolated compounds. I’ve also found it supports my mood and reduces some of the scattered thinking I struggle with due to ADHD. If you’re looking for a natural cognitive boost that actually feels clean and sustainable, this is it. I truly love it and recommend it to anyone who wants better brain health—without the crash or side effects.
C**S
Amazing
I had nerve damage and started taking this daily. I swear I healed faster than I would have ilif I didn't take it. The doctors said it could be a year and my nerves made significant improvement within months.
M**Y
Quality
Quality product.. it seems to help rain fog memory.
M**T
Hard to tell if a product like this is good or not. It did not make me sick but maybe only placebo effect
B**R
This is medicine for memory enhancement. It’s not the first time I am using it. It’s a product procured from the USA. I was impressed with the time they took for delivery. Helped me a lot.
S**I
Reliable product from world famous fungus expert Paul Stamets
A**R
It would be nice to have 60 pills in one bottle, since the daily dose is 2 pills. Less plastic needed. I can see my brain performing much better. After my second pregnancy it is noticeable how the brain looses a little bit its tuning.
M**A
me ha ayudado mucho, traía una pesadez de cerebro, que se me quito desde que tomo la melena de Leon, me parece muy buen producto
Trustpilot
5 days ago
2 months ago