

🦷 Elevate your smile game with Japan’s enamel-boosting secret!
APAGARD® M-Plus is a fluoride-free toothpaste featuring Sangi’s original nano-Hydroxyapatite, scientifically designed to repair enamel, remove surface stains, and reduce sensitivity. This mild mint-flavored formula is Japan’s top-selling hydroxyapatite toothpaste, now available in the US, offering a safe, effective, and family-friendly solution for naturally whiter teeth and fresher breath.
| ASIN | B0F1FMTJXR |
| Best Sellers Rank | #45,899 in Health & Household ( See Top 100 in Health & Household ) #578 in Toothpaste |
| Customer Reviews | 4.7 4.7 out of 5 stars (81) |
| Date First Available | March 14, 2025 |
| Manufacturer | SANGI CO.,LTD |
| Package Dimensions | 7.32 x 1.93 x 1.77 inches; 5.61 ounces |
L**E
Definitely buying again
Great product, I've seen a tremendous improvement on my teeth, it actually feels clean. It does have a whitening effect and the taste is acceptable. The ingredients are just what I expected, this product is worth it and would definitely buy again.
E**S
Game Changer for Sensitive Teeth
I’ve purchased this multiple times and it’s still my absolute favorite toothpaste. I struggle with pretty intense tooth sensitivity, and this is honestly the only toothpaste I’ve ever tried that makes such a dramatic difference. It took my hyper-sensitive teeth to hardly feeling sensitive at all. The key for me has been using it consistently—I noticed a real improvement about halfway through my first tube. I typically brush, then do a very light rinse and avoid rinsing around my teeth so the paste can keep working. It also leaves my mouth feeling super fresh and clean. After finishing Invisalign, I had a huge spike in sensitivity and this helped resolve it more than anything else. Highly recommend if you deal with sensitive teeth!
N**E
Excellent toothpaste
Best toothpaste I have ever used to date. There are several toothpastes that whiten your teeth, help prevent plaque build up, improve gum health, reduce sensitivity, strengthen enamel, even claim to remove tartar ( slowly ). To say that the market is overhyped is putting it mildly. There are toothpastes made with neem (excellent at keeping plaque at bay, xylitol which prevents the bio film from sticking. Every kind of fluoride ( Sodium fluoride, sodium mono fluoro phosphate, stannous fluoride ….). Then there are toothpastes for tooth sensitivity ( potassium nitrate or arginine bicarbonate ). Now for those of use that prefer to use a toothpaste which does not contain a fluoride, there are the nano hydroxy apatite versions. As expected there are a range of claims and each has its adherents. I suffered for several weeks following the fitting of 2 crowns from a very unusual pain / feeling of tightness in my gums. Tried just about every toothpaste and mouthwash ( including chlorhexidine ). Nothing seemed to help until I tried Boka nano hydroxy toothpaste. Within 2 days I noticed a difference. Then I learnt of the Apgard M plus and the premio. I tried the M plus and noticed that the rate of improvement in my gum issue accelerated. Look I know there are all kinds of claims and counterclaims. You need at least 10% nano hydroxy apatite. The size and shape of the nanoparticle matters. Some claim SLS and other additives are unwanted, others say they are best present to create foam … The bottom line M plus in its current form is been in production since 1985. The Japanese manufacturer bought out the original NASA patent. It works. By far the best I have experienced for tooth sensitivity, gum health, keeping the enamel free of plaque. Is it as good as the premio or higher versions. I don’t know, I have never tried them. This version works well. Brush your teeth twice a day at least for at least 2-3 minutes, rinse lightly and spit out. Are there other equivalent or better options out there. ( Dr Jens, Ollie, … ) very possibly. All I can say is that I never expected a toothpaste to have such noticeable improvements on my teeth and gums. To me the fact that it’s made by the Japanese who are known for quality and reproducible process control, is a plus. I am satisfied.
R**L
High quality
I do feel like my teeth are slightly whiter with this toothpaste. It’s subtle but I do feel better knowing I am not using Flouride.
J**L
It’s worth the money
It really shows a difference in the sensitivity, the taste is not strong or overpowering, and I see a difference in whiteness of teeth!! I would definitely recommend trying it!
W**!
Decent premium toothpaste
I’ve been using this stuff for a couple of years now. I’m not sure how effective it is in preventing cavities or healing my teeth, but it makes me feel good and it doesn’t have any fluoride in it and it tastes pretty good. Better safe than sorry and this is a good deal for two tubes of toothpaste.
C**S
Wonderful
Amazing product. Almost immediate results.
C**S
Worth it
Worth the price ! Teeth have lightened at least 2-3 shades. Love the taste and my teeth feel dentist clean .
Trustpilot
2 weeks ago
4 days ago