Batch HPLC tested at 99%+ purity. Store frozen long term or in fridge when ready to be used. Sold for research purposes only. Contact us for Wholesale Orders. Download COA here: VIP COA.pdf Please note if you have a different Batch ID please contact us for the latest COA. VIP Vasoactive Intestinal Peptide (VIP) Chemical Identifiers IUPAC Name: (2S)-4-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-4-methylsulfanylbutanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoic acid Molecular Formula: C147H237N43O43S CAS Number: 17038-86-9 PubChem CID: 16132300 Molecular Structure Vasoactive Intestinal Peptide (VIP) is a 28-amino acid peptide, part of the glucagon/secretin superfamily. Its amino acid sequence is: His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Cys-Gly-Thr-Pro-Gly-Ala-Gly-Glu-Glu-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly VIP adopts an alpha-helical structure stabilized by disulfide bonds between cysteine residues. Gene and Protein Information Gene Symbol: VIP Gene ID: 7432 (NCBI Gene Database) Protein ID: P01282 (UniProt) Organism: Homo sapiens Receptor Interaction VIP binds to G protein-coupled receptors VPAC1 (VIPR1) and VPAC2 (VIPR2), expressed in various tissues including brain, lung, gastrointestinal tract, and immune cells. Binding induces increased intracellular cyclic AMP (cAMP) and downstream signaling pathways. References Vasoactive Intestinal Peptide. PubChem Compound Summary for CID 16132300. https://pubchem.ncbi.nlm.nih.gov/compound/Vasoactive-Intestinal-Peptide UniProtKB – P01282 (VIP_HUMAN). https://www.uniprot.org/uniprotkb/P01282/entry VIPR1 – Vasoactive Intestinal Polypeptide Receptor 1 – Homo sapiens (Human). UniProtKB. https://www.uniprot.org/uniprotkb/P32241/entry VIPR2 – Vasoactive Intestinal Polypeptide Receptor 2 – Homo sapiens (Human). UniProtKB. https://www.uniprot.org/uniprotkb/P41587/entry Vasoactive Intestinal Peptide. Wikipedia. https://en.wikipedia.org/wiki/Vasoactive_intestinal_peptide Keywords: VIP, Vasoactive intestinal peptide.
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