Biotrue Hydration Boost Preservative-Free Eye Drops 0.33 Fl oz 2 pack

This is a combination review of a handful of preservative free eye drops. This is by no means extensive nor thorough. There are many others on the market that I have yet to try, but these were the ones I believed to be most relevant to my needs, which consist of relief after PRK surgery. Drops reviewed: Refresh Relieva for contacts Systane Gel Drops Systane Hydration PF Biotrue Systane Ultra PF Oasis Tears Plus I will cross post this on each of the other drops' pages. I will review the drops based on relief, perceived longevity, consistency, ease of use, and relevant features. At the time of this review, I am at exactly one month post surgery. I will be rating each of these drops 5 stars on their relevant pages because they all do exactly what they're designed to do and don't have any glaring issues that warrants fewer than 5 stars. The in-post reviews are relevant to comparing between these drops. Refresh Relieva (5 stars): These drops are fantastic. I find that I want to reach for these the most often when I'm looking for good eye lubrication. These drops spread over my eye very quickly without feeling like they stick to the edges of my eyes or eyelashes. Out of all the drops other than the gel, these drops feel like they last the longest in between drops. I use this the least often and find great relief for about half an hour before I want to use them again. These drops feel less slimy than the other drops except for Biotrue. Out of all of the other bottles, it's the most traditional dropper and easiest to use, but due to the design, it may be most susceptible to contaminants and early expiration. It's the only bottle that I'm able to fit my nanodropper onto and that will potentially mitigate the potential contamination and as a result, will prevent early expiration as well as extend the number of drops due to the smaller drops the nanodropper creates. Overall, these are my favorites drops. Systane Gel (3 stars): Out of all of the drops, I reach for these least often. I thought I might try them to see if they last longer and provide the longest lasting relief. If that's what you're looking for, these drops are great, except there are drawbacks that cause me to not use them. They're sticky. If I fall asleep with them in, my eyelids get a little glued together and I sometimes have to pick the gel out of my eyelashes and that can be very uncomfortable. They provide a great deal of relief for the longest period of time and that's the saving grace for these drops, but I'd rather not deal with the slime I get all over my face when I inevitably rub my eyes due to the uncomfortable residue that sits on the edges of my eyes and eyelashes. This dropper is very easy to use and on par with the Refresh dropper. I have no complaints about the amount it drops and the ease of use. Systane Hydration (5 stars): These drops are a very close second to Refresh overall. The relief is only noticeably less than Refresh because the Refresh feels so good. These are exactly what I would expect from a high quality drop and would not be disappointed if these were the only drops available to me. They last about 20-30 minutes and are easy to use. The consistency of these drops is pretty thin. They're only ever so slightly thicker than Biotrue, Ultra, and Refresh. The dropper produces a slight bit of waste if you don't stop squeezing at the right moment but is otherwise very easy to use. Overall, my second favorite drops to use. Biotrue (4 stars): The relief that these drops provide are comparable to Refresh except they don't last as long. I end up having to use these fairly frequently because they don't last very long. I've been using these drops just to get through the bottle. These drops just feel slightly inferior to Systane Hydration in almost every aspect. They go on very nicely and don't stick to my eyelashes or the edges of my eyes as much as Systane, but they don't last as long, provide comparable relief, and the bottle is far more difficult to use. The consistency is the thinnest out of all these drops. This bottle has a special technology that requires a great deal of force to squeeze out a drop. Despite that, the bottle creates a significant amount of waste no matter how you squeeze it, and you have to squeeze it pretty hard. This bottle is my least favorite to use even if the drops are pretty decent. Overall, these are my second to last choice only beating the gels. Systane Ultra PF (5 stars): I think that if I had gotten these in a bottle, they'd be my second favorite to use. They're my go-to for when I'm on the go and need portable drops. They provide a great deal of relief and give about 30 minutes of lubrication. I almost always grab a few of these if I'm going to be out of the house for an extended period of time. The consistency is thin and far less slimy than Hydration. I find that they coat my eye very well and don't stick to my eyelashes and the edges of my eyes. My only issue with these is that they create a significant amount of waste compared to the bottles. I also end up dropping them or losing them when they drop out of my pockets, but they serve a purpose. There's always some product that gets stuck in the twist off cap, so that's a problem too. They're great for transport though, and if I had a bottle, I'd probably prefer it over Hydration. Overall, I really like these drops but I feel bad about the waste. Oasis Tears Plus (3 stars): I feel like these drops are the standard for high quality drops. They provide a fair amount of relief, they last a fair amount of time (roughly 20 minutes), and they're the second most thick drops only less thick than the gel. I don't think I'd get these drops again with these other options. I don't dislike them, but they just don't provide the same amount of relief and longevity as some of the other options. It's also smaller than the Ultra so I get fewer drops out of them. They seem to be smaller so they produce less waste, but not by much. They're very easy to use, but all of these disposable drops produce waste of materials and some product gets stuck in the twist cap, so there's always waste there as well. The Ultra is no different. Overall, I'd probably never use these unless they serve a particular purpose that I'm unaware of.

I'm writing this review because I INSTANTLY felt relief from these drops and knew I needed to share my experience. I've been using Systane Eye Drops for the past several years based on my doctor's recommendation for my dry eyes, but those drops would always leave my eyes with an initial burning sensation that would make my eyes uncomfortable and blurry for about 2-3 minutes. With these Biotrue drops, there was no burning, and my eyes felt instantly soothed instead! As a daily, heavy computer user, I waited about an hour after the initial drops that I used to write this.... and I'm happy to confirm that my eyes still feel hydrated and not irritated. Super happy with this purchase and will be reordering once I'm low.

I have no problem with the bottles as many reviewers complain and I am 76 with decreased manual dexterity and constantly drop things. I find the cap fine and no problem squeezing out a couple drops. I also think this design cap keep the bottles sterile. BioTrue dry eye drops work really well for me with very dry eyes and feel so refreshing and not sticky afterward. First time using almost felt like super clean purified water I sometimes use an Allergy eye drop during bad allergy season and my eyed become unbearably scratchy. I found HydraSense Allergy Complete from CTC Canada. Works as well as Similisan. For many years used Similisan drops made in Switzerland but it is homeopathic classified and USA no longer permits its sale. Very annoying to have to order from Canada and pay $15 postal and it is often out of stock. Similisan has great products. Their Allergy eyes drops are awesome too preservative free. . So had to find alternatives that don’t burn my sensitive dry eyes. I had to stop wearing contacts 30 years ago due to dry eye. Recently started using Optive vials but they sometimes leave my eyes feeling blurry almost sticky like. After several months of using my eyes became red so I wondered if I developed an allergy to Optive. BioTrue very good. Only drawback vs vials, with a single bottle if you take it with you and lose it you have a real problem which I just did. So will keep 2 on hand. I have to do drops at least 2x a day and warm wet compress on my eyes per my Ophthalmologist when I get up in the morning. So far no irritation and eyes happier.

The bottle always squeezes more than a drop and it gets stuck at the dropper. I have to literally touch my eye to not waste the residuals. Sometimes it’s a huge drop, other times it’s a mini drop. Then the bottle shrinks overtime making it More difficult to squeeze

These things are great. I love the hydration boost contact solution they have. I unfortunately stopped wearing contacts for a year and only had generic contact solution in the house. I was dreading wearing my contacts every day because they would be so dry after a few hours. Usual eye drops that say they can be used with contacts often do not make a difference but these things really do work! They work so good. I keep some on me everywhere. I gave some the other day to someone at work who wears glasses that was complaining of dry eyes and they loved them as well. The size is the perfect amount of solution to apply multiple times, even after you blink and some needs to be patted away with a tissue, you still have more left over. There is no noticable difference in texture, other than it helps your eyes feel instant relief. It does not make your eyes feel grainy or oily. I will be buying these over and over again.

I have had dry, scratchy, burning eyes for 40 years. Hypo-Tears worked for many years until it was discontinued. Then I began the search for a replacement, which was not at all easy. It was an expensive ordeal to buy so many different eyedrops, only to find they did not work, or even made the dryness and scratchiness WORSE. I tried Rx brands Restasis, Xiidra, Miebo. None helped. In fact, the Restasis seemed to make me feel unwell in general. Did not expect a whole-body feeling of unwellness from an eye drop. I get angry when I see eye "ointments" marketed for dry eyes. They are just petrolatum (vaseline). You can't even SEE once you've smeared petrolatum into your eye. It's greasy and gross. It's going to stain your pillowcase, and doesn't provide any relief whatsoever. Ointments are junk. Unless you put it into your pet's eyes before bathing to protect their eyes from shampoo. I need eyedrops before I go to sleep, in fact my eyes are so dry that if not adequately lubricated at bedtime, they will WAKE ME UP in the middle of the night from the scratchy discomfort of REM while I'm trying to sleep. I have eye drops in every room of the house, in all handbags, at work, and never leave home without them. I tried a new ophthalmologist 2 years ago. He had some interesting advice. He said to try to avoid eyedrops with preservatives, saying that they can build up in your system, potentially causing additional problems. This I took seriously. And then I tried all the preservative-free brands. Most provided no relief. This Biotrue Hydration Boost (green box) is the best solution I have found. I seem to need it less often, which must mean it's more effective. I have pretty much abandoned my dozens of other brands in favor of this one. So it's a big deal to finally receive some relief, and to know that it's preservative-free. I highly recommend. I'm happy to find it on Amazon for a reasonable price, I buy the 2-pack. However, I HATE the bottle. The cap is not user-friendly, and neither is the bottle. Some bottles had to be squeezed SO hard to dispense a drop that they made my fingers ache. After struggling for too long, I found a slender needle, disinfected it, and poked it into the tip, which worked to allow the drops to flow more freely. I would also prefer a flatter-shaped bottle, so that it would better fit into your pocket. I hope the manufacturer sees this. Please improve the bottle!

There is nothing wrong with the eye drop solution itself which feels just fine. Getting a drop to dispense out of the container requires forced sustained indentation of the container to half its normal diameter such that it feels the bottle itself might just break completely open---all that effort for one mere drop. I will not purchase this product again simply because it is way too difficult to dispense.

I purchased this for occasional dry and uncomfortable eyes, and it has worked very well. Whenever my eyes feel stiff, irritated, or overly dry, using this provides fast and noticeable relief. The moisturizing effect feels immediate, and my eyes feel much more comfortable shortly after use. I also appreciate that it is preservative-free, which makes it feel gentler and more suitable for repeated use when needed. That was an important reason I chose it. The drops feel clean and refreshing rather than heavy or overly medicated. It gives hydration without leaving an unpleasant residue or blurry feeling for long. This has become one of those items I like to keep nearby at home or during workdays when screen time causes eye fatigue. Overall, this has been highly effective whenever my eyes feel dry or strained. I would definitely buy it again. Five stars.