---
product_id: 720262145
title: "APAGARD® M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth. Fluoride-Free, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Single Pack"
brand: "apagard"
price: "AR$88747"
currency: ARS
in_stock: true
reviews_count: 8
category: "Apagard"
url: https://www.desertcart.com.ar/products/720262145-apagard-m-plus-sangis-nano-hydroxyapatite-toothpaste-for-naturally-whiter
store_origin: AR
region: Argentina
---

# Natural stain removal & whitening Fluoride-free, gentle for sensitive teeth Nano-Hydroxyapatite enamel repair APAGARD® M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth. Fluoride-Free, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Single Pack

**Brand:** apagard
**Price:** AR$88747
**Availability:** ✅ In Stock

## Summary

> 🦷 Elevate your smile game with Japan’s enamel-boosting secret!

## Quick Answers

- **What is this?** APAGARD® M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth. Fluoride-Free, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Single Pack by apagard
- **How much does it cost?** AR$88747 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.com.ar](https://www.desertcart.com.ar/products/720262145-apagard-m-plus-sangis-nano-hydroxyapatite-toothpaste-for-naturally-whiter)

## Best For

- apagard enthusiasts

## Why This Product

- Trusted apagard brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Trusted & Proven Formula:** Japan’s longest-selling hydroxyapatite toothpaste, now elevating oral care in the US.
- • **Gentle Yet Effective Whitening:** Removes surface plaque and everyday stains without harsh chemicals.
- • **Fluoride-Free & Family Friendly:** Safe for all ages, perfect for sensitive teeth and daily use.
- • **Long-Lasting Freshness & Breath Care:** Mild mint flavor keeps your mouth feeling clean and confident all day.
- • **Revolutionary Nano-Hydroxyapatite Technology:** Japan’s patented enamel-building breakthrough for a naturally stronger smile.

## Overview

APAGARD® M-Plus is a fluoride-free toothpaste featuring Sangi’s original nano-Hydroxyapatite, scientifically designed to repair enamel, remove surface stains, and reduce sensitivity. This mild mint-flavored formula is Japan’s top-selling hydroxyapatite toothpaste, now available in the US, offering a safe, effective, and family-friendly solution for naturally whiter teeth and fresher breath.

## Description

Ingredients (INCI name): DICALCIUM PHOSPHATE, AQUA, GLYCERIN, SILICA, HYDROXYAPATITE, PEG-8, SODIUM LAURYL SULFATE, CELLULOSE GUM, AROMA, TRIMAGNESIUM PHOSPHATE, PVP, HYDROLYZED CONCHIOLIN PROTEIN, SODIUM SACCHARIN, GLYCYRRHETINIC ACID, CETYLPYRIDINIUM CHLORIDE, LAURYL DIETHYLENEDIAMINOGLYCINE HCL

Review: Definitely buying again - Great product, I've seen a tremendous improvement on my teeth, it actually feels clean. It does have a whitening effect and the taste is acceptable. The ingredients are just what I expected, this product is worth it and would definitely buy again.
Review: Game Changer for Sensitive Teeth - I’ve purchased this multiple times and it’s still my absolute favorite toothpaste. I struggle with pretty intense tooth sensitivity, and this is honestly the only toothpaste I’ve ever tried that makes such a dramatic difference. It took my hyper-sensitive teeth to hardly feeling sensitive at all. The key for me has been using it consistently—I noticed a real improvement about halfway through my first tube. I typically brush, then do a very light rinse and avoid rinsing around my teeth so the paste can keep working. It also leaves my mouth feeling super fresh and clean. After finishing Invisalign, I had a huge spike in sensitivity and this helped resolve it more than anything else. Highly recommend if you deal with sensitive teeth!

## Features

- Japan’s Leading Hydroxyapatite Toothpaste is now in the US. APAGARD features Sangi’s original nano-Hydroxyapatite (nano-mHAP), delivering Japan’s ground-breaking oral care expertise to your daily routine.
- Cleans Teeth & Helps Remove Surface Plaque. With consistent brushing, APAGARD nano-Hydroxyapatite toothpaste helps remove plaque and everyday stains, giving you a naturally brighter smile.
- APAGARD M-plus is the standard, classic version and longest-selling product in the APAGARD range. It offers an all-around balance between natural whiteness enhancement, breath care, and stain control, and is suited for all ages, coming in a higher volume package ideal for family use.
- Contains SANGI's Original nano-Hydroxyapatite -the building block of tooth enamel- , which was first synthesized by SANGI Co.,Ltd in 1978.
- For optimal effect from your nano-mHAP toothpaste, we recommend that you (1) Place a small amount (1-1.5 cm/ 0.4-0.6 inch) on a toothbrush. (2) Brush your teeth and gums gently but meticulously for about 3-5 minutes, ideally after each meal (3 times/ day is recommended). (3)Rinse lightly and spit out after brushing, avoiding excessive rinsing.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B0F1FMTJXR |
| Best Sellers Rank | #45,899 in Health & Household ( See Top 100 in Health & Household ) #578 in Toothpaste |
| Customer Reviews | 4.7 4.7 out of 5 stars (81) |
| Date First Available  | March 14, 2025 |
| Manufacturer  | SANGI CO.,LTD |
| Package Dimensions  | 7.32 x 1.93 x 1.77 inches; 5.61 ounces |

## Product Details

- **Age Range (Description):** All Ages
- **Brand:** APAGARD
- **Flavor:** Mild Mint
- **Item Form:** Paste
- **Material Feature:** Natural

## Images

![APAGARD® M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth. Fluoride-Free, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Single Pack - Image 1](https://m.media-amazon.com/images/I/61DmvslT4YL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Definitely buying again
*by L***E on July 27, 2025*

Great product, I've seen a tremendous improvement on my teeth, it actually feels clean. It does have a whitening effect and the taste is acceptable. The ingredients are just what I expected, this product is worth it and would definitely buy again.

### ⭐⭐⭐⭐⭐ Game Changer for Sensitive Teeth
*by E***S on January 14, 2026*

I’ve purchased this multiple times and it’s still my absolute favorite toothpaste. I struggle with pretty intense tooth sensitivity, and this is honestly the only toothpaste I’ve ever tried that makes such a dramatic difference. It took my hyper-sensitive teeth to hardly feeling sensitive at all. The key for me has been using it consistently—I noticed a real improvement about halfway through my first tube. I typically brush, then do a very light rinse and avoid rinsing around my teeth so the paste can keep working. It also leaves my mouth feeling super fresh and clean. After finishing Invisalign, I had a huge spike in sensitivity and this helped resolve it more than anything else. Highly recommend if you deal with sensitive teeth!

### ⭐⭐⭐⭐⭐ Excellent toothpaste
*by N***E on October 14, 2025*

Best toothpaste I have ever used to date. There are several toothpastes that whiten your teeth, help prevent plaque build up, improve gum health, reduce sensitivity, strengthen enamel, even claim to remove tartar ( slowly ). To say that the market is overhyped is putting it mildly. There are toothpastes made with neem (excellent at keeping plaque at bay, xylitol which prevents the bio film from sticking. Every kind of fluoride ( Sodium fluoride, sodium mono fluoro phosphate, stannous fluoride ….). Then there are toothpastes for tooth sensitivity ( potassium nitrate or arginine bicarbonate ). Now for those of use that prefer to use a toothpaste which does not contain a fluoride, there are the nano hydroxy apatite versions. As expected there are a range of claims and each has its adherents. I suffered for several weeks following the fitting of 2 crowns from a very unusual pain / feeling of tightness in my gums. Tried just about every toothpaste and mouthwash ( including chlorhexidine ). Nothing seemed to help until I tried Boka nano hydroxy toothpaste. Within 2 days I noticed a difference. Then I learnt of the Apgard M plus and the premio. I tried the M plus and noticed that the rate of improvement in my gum issue accelerated. Look I know there are all kinds of claims and counterclaims. You need at least 10% nano hydroxy apatite. The size and shape of the nanoparticle matters. Some claim SLS and other additives are unwanted, others say they are best present to create foam … The bottom line M plus in its current form is been in production since 1985. The Japanese manufacturer bought out the original NASA patent. It works. By far the best I have experienced for tooth sensitivity, gum health, keeping the enamel free of plaque. Is it as good as the premio or higher versions. I don’t know, I have never tried them. This version works well. Brush your teeth twice a day at least for at least 2-3 minutes, rinse lightly and spit out. Are there other equivalent or better options out there. ( Dr Jens, Ollie, … ) very possibly. All I can say is that I never expected a toothpaste to have such noticeable improvements on my teeth and gums. To me the fact that it’s made by the Japanese who are known for quality and reproducible process control, is a plus. I am satisfied.

## Frequently Bought Together

- APAGARD® M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Pack of 1
- Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 1Pk US Manufactured
- Apagard Tooth Polish Royal 135g toothpaste, Direct from Japan

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*Product available on Desertcart Argentina*
*Store origin: AR*
*Last updated: 2026-01-22*