--- product_id: 117698062 title: "FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 8" brand: "frontline" price: "AR$287907" currency: ARS in_stock: true reviews_count: 12 category: "Frontline" url: https://www.desertcart.com.ar/products/117698062-frontline-plus-flea-and-tick-spot-treatment-for-large-breed store_origin: AR region: Argentina --- # Waterproof after 24 hrs Month-long protection Fast-acting in 24 hrs FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 8 **Brand:** frontline **Price:** AR$287907 **Availability:** ✅ In Stock ## Summary > 🐾 Protect your best friend like a pro — no fleas, no ticks, no worries! ## Quick Answers - **What is this?** FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 8 by frontline - **How much does it cost?** AR$287907 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.com.ar](https://www.desertcart.com.ar/products/117698062-frontline-plus-flea-and-tick-spot-treatment-for-large-breed) ## Best For - frontline enthusiasts ## Why This Product - Trusted frontline brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Waterproof Defense:** Keeps working even if your dog gets wet after 24 hours - • **Break the Flea Cycle:** Kills adult fleas, eggs, larvae & ticks for full lifecycle control - • **Trusted for 20+ Years:** Proven reliability with millions of happy pets worldwide - • **Effortless Monthly Care:** Easy single-spot application for 30 days of protection - • **Tailored for Large Dogs:** Specifically formulated for dogs 45 to 88 lbs to ensure optimal dosing ## Overview FRONTLINE Plus Flea and Tick Treatment offers fast, waterproof, and long-lasting protection for large dogs (45-88 lbs). Using a proven formula of fipronil and (S)-methoprene, it kills fleas, ticks, lice, mites, and flea eggs/larvae, breaking the infestation cycle with just one monthly topical application. Trusted by pet owners for over 20 years, it’s easy to apply and keeps your dog comfortable and pest-free all season long. ## Description Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention. Review: Finally found something that actually works! - After trying at least four different flea treatments that barely made a dent, I'm so relieved to have found these drops. They actually work - and work fast. We have two dogs who love being outside, and fleas have been an ongoing battle, especially during the warmer months. Within 24 hours of applying these drops, I noticed a huge difference. The scratching stopped, and when I checked them over, the fleas were gone. It's been several weeks now and still no sign of them coming back. Application is easy - just part the fur at the back of the neck and squeeze the tube. My dogs don't seem bothered by it at all, and it dries quickly so they can go about their day. The protection lasts the full month as advertised, which is more than I can say for some of the other brands we've tried. I've set up a subscription so I never run out because I'm not going back to the constant scratching and discomfort my pups were dealing with before. If you've been struggling to find an effective flea treatment, I highly recommend giving these a try. They've been a game-changer for us. Worth every penny for the peace of mind and happy, comfortable dogs! Review: Works well! Keeps the ticks from embedding. - This works very well on my 10 year old Golden Retriever. He is a “tick magnet” and when this medication is applied, the ticks will not embed on him. He never has a flea problem so I can’t speak to whether it works for fleas. It does not cause any skin irritation and has no odor. It seems to last the full month before ticks become a problem again. ## Features - The #1 name in flea and tick protection - Trusted by pet owners for over 20 years** - Fast-acting, long-lasting flea and tick treatment thats waterproof 24 hours after application - Protects from fleas and ticks for a full month - Kills adult fleas, flea eggs, flea larvae, ticks, and chewing lice - Aids in the control of sarcoptic mange infestations - Stops existing flea infestations and prevents establishment of new infestations ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B07NGNFCCJ | | Active Ingredients | fipronil and (S)-methoprene | | Age Range Description | All Life Stages | | Allergen Information | Gluten Free | | Best Sellers Rank | #80 in Pet Supplies ( See Top 100 in Pet Supplies ) #2 in Dog Flea Drops | | Brand | Frontline | | Brand Name | Frontline | | Customer Reviews | 4.4 out of 5 stars 49,969 Reviews | | Dog Breed Size | Large | | Included Components | Applicator | | Item Form | Liquid | | Item Type Name | Topical Purple box | | Item Volume | 12 Milliliters | | Item Weight | 2.4 ounces | | Manufacturer | Boehringer Ingelheim Animal Health | | Manufacturer Part Number | 72219 | | Model Number | 72219 | | Scent | Unscented | | Scent Name | Unscented | | Target Species | Dog | | UPC | 350604062462 611030624625 | | Unit Count | 1 Count | | Volume | 12 Milliliters | | Warranty Description | If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842. | ## Product Details - **Active Ingredients:** fipronil and (S)-methoprene - **Age Range (Description):** All Life Stages - **Allergen Information:** Gluten Free - **Brand:** Frontline - **Dog Breed Size:** Large - **Item Form:** Liquid - **Item Volume:** 12 Milliliters - **Item Weight:** 0.15 Pounds - **Scent:** Unscented - **UPC:** 350604062462 611030624625 ## Images ![FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 8 - Image 1](https://m.media-amazon.com/images/I/71QQ2+8FjsL.jpg) ![FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 8 - Image 2](https://m.media-amazon.com/images/I/81HWNyMk9sL.jpg) ![FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 8 - Image 3](https://m.media-amazon.com/images/I/814CcTxB26L.jpg) ![FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 8 - Image 4](https://m.media-amazon.com/images/I/814n+7Kn+kL.jpg) ![FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 8 - Image 5](https://m.media-amazon.com/images/I/81dlsY2VC9L.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: "hola buenas tardes, compre este producto pero no veo o no sale la fecha de caducidad ( vencimiento ) del producto "** A: Siempre que lo mantenga a temperatura ambiente y sellado en su empaque original, FRONTLINE Plus permanecerá listo para la batalla! **Q: Hi. We only need one treatment for 3 dogs. 135lbs, 105lbs and 50lbs. Any suggestions on how one package would work? Thanks!** A: You need to buy for the dogs pound. The extra large would cover you biggest dogs but the 50 pound dog needs a different package. I recommend you dont try to mix up the weight dosages. Its chemical and i have seen the result of too much flea chemicals on a cat. My opinion is buy the weight size that fit your dog. Then you will be safe Never had a problem with this flea treatment at all works great! **Q: is there a flea and tick combined to prevent heart worm** A: Those are typically by perscription only from a vet, but yes there are. **Q: i recieved an email saying this exact product selected from my "buy again" bin,was fake.why is it here?!** A: Tom, I am not absolutely certain why it would still be on your order list. I did not use the "buy it again" button because I had the same fake stuff that you apparently had. I did a search and treated the transaction like I had never had the bad stuff. What I have this time appears to be the real thing. A couple of stickers from Frontline about how this is their product and it looks a lot more like the actual Frontline product. The other stuff was too viscous and really did not come out of the applicator very well. Of course, the dog kept scratching which was a good clue that something was wrong. A lot better experience this time. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Finally found something that actually works! *by R***Z on February 9, 2026* After trying at least four different flea treatments that barely made a dent, I'm so relieved to have found these drops. They actually work - and work fast. We have two dogs who love being outside, and fleas have been an ongoing battle, especially during the warmer months. Within 24 hours of applying these drops, I noticed a huge difference. The scratching stopped, and when I checked them over, the fleas were gone. It's been several weeks now and still no sign of them coming back. Application is easy - just part the fur at the back of the neck and squeeze the tube. My dogs don't seem bothered by it at all, and it dries quickly so they can go about their day. The protection lasts the full month as advertised, which is more than I can say for some of the other brands we've tried. I've set up a subscription so I never run out because I'm not going back to the constant scratching and discomfort my pups were dealing with before. If you've been struggling to find an effective flea treatment, I highly recommend giving these a try. They've been a game-changer for us. Worth every penny for the peace of mind and happy, comfortable dogs! ### ⭐⭐⭐⭐⭐ Works well! Keeps the ticks from embedding. *by A***R on April 21, 2026* This works very well on my 10 year old Golden Retriever. He is a “tick magnet” and when this medication is applied, the ticks will not embed on him. He never has a flea problem so I can’t speak to whether it works for fleas. It does not cause any skin irritation and has no odor. It seems to last the full month before ticks become a problem again. ### ⭐⭐⭐⭐⭐ This is hands-down the best flea and tick preventative made *by L***S on January 12, 2016* This is hands-down the best flea and tick preventative made. I've tried others, such as Revolution, and would end up having to pick literally 20-50 attached ticks off my dog every time we went hiking and that was pretty much every day. Then they'd get in the house and be crawling on bedsheets and even across the keyboard of the computer - total nightmare. Since using Frontline, I rarely find any. Once in a while I'll find one or maybe two, but they're crawling on top of her fur and never attached. Since using Frontline, I haven't once found an attached tick on my dog nor my mom and dad's dog who is also treated with Frontline. They have had the same experience with their dog - the other brands just plain don't work - at least not for ticks, which is the main issues that we deal with, being that we live in the mountains and hike with the dogs almost ever day. Frontline works. Period. My only caveat is that you can't use this for people, which tells me that it's pretty toxic and that's why I'm giving it 4 stars instead of 5. It's pretty nasty stuff, you're supposed to avoid getting in on your skin and wash your hands immediately afterwards. If it's that toxic to humans, how safe can it be for our dogs? I really don't like the idea of putting something that's too toxic for humans on my dog and neither do my mom and dad. If we lived in the city and/or ticks weren't such an issue, we wouldn't use it. However, because of where we live and our lifestyle, the risks of tick-borne diseases outweigh the risks of the toxicity of the medicine. It's worth it for us. Decide for yourself if it's worth it for you. ## Frequently Bought Together - Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs., 8 Treatments - Frontline Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 6 Treatments - Frontline Plus for Dogs Medium Dog (23-44 pounds) Flea and Tick Treatment, 6 Doses --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.com.ar/products/117698062-frontline-plus-flea-and-tick-spot-treatment-for-large-breed](https://www.desertcart.com.ar/products/117698062-frontline-plus-flea-and-tick-spot-treatment-for-large-breed) --- *Product available on Desertcart Argentina* *Store origin: AR* *Last updated: 2026-05-17*